EA had several cool looking trailers and demos. My favourites were Mass Effect 3 (of course) and the epic CG trailer for The Old Republic. Battlefield 3, although not my kind of game, looked insane as well. New Need for Speed was a surprise, especially the action outside of the car.
Ubisoft had an OK show too despite the annoying Mr. Caffeine, random mic problems and strange French presenters :P The Rayman Origins demo was really cute and fun. Assassin's Creed trailer and demo kicked a$$. I also enjoyed the beginning of the FarCry 3 demo. What the hell was up with the new Brothers in Arms? It looked really stupid, but if done right it can be absolutely hilarious. I'm not convinced yet...
Been watching Gametrailers TV a lot too, and I absolutely loved the Skyrim demo as mentioned earlier. I'm also psyched about the new The Darkness game as I loved the original (and the demo looked great). New Arkham looks great as well, I need to play Arkham Asylum first though :P